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Menopause and Heart Disease

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Heart disease is the number one killer of women today. Dr. Chrisandra Shufelt, assistant director of the Women’s Heart Center at the Cedars-Sinai Heart Institute, shares valuable information about heart disease during menopause.

Interview with Chrisandra Shufelt, M.D.
Assistant Director of the Women’s Heart Center
at the Cedars-Sinai Heart Institute.

1. Question: How can women approaching or experiencing menopause protect themselves from heart disease?

Chrisandra Shufelt, M.D.: The best protection is in knowing your heart health numbers. By that I mean you should know your blood pressure, LDL and HDL cholesterol, weight, body mass index (BMI) and fasting blood sugar level. If your numbers are out of whack, see your doctor, start exercising, change your eating habits, lose weight if you need to and stop smoking. You also need to be aware of your family medical history. Women who have a first-degree relative diagnosed with heart disease at an early age are at an increased risk of developing heart disease themselves. Heart disease is the number one killer of women so the first step in preventing it is to know your numbers.

2. Question: Does a woman’s heart disease risk increase during menopause?

Dr. Shufelt: One in seven premenopausal women die of heart disease compared to one in three postmenopausal women. We know that blood cholesterol levels can often change for the worse within six months to a year from the onset of menopause, which on average is the age of 51. The risk of high blood pressure triples with menopause; after the age of 55, more women have high blood pressure.

3. Question: Does hormone therapy increase a woman’s risk of developing heart disease?

Dr. Shufelt: Hormone therapy may be an effective way of controlling the moderate to severe night sweats, hot flashes and other menopause symptoms that can wreak havoc in a woman’s life. Start by seeking a certified menopause specialist who can weigh the risks and benefits for each patient. If your doctor considers hormone therapy safe for you, be sure to reevaluate annually. Starting hormone therapy many years after a woman has gone through menopause does increase the risk of heart disease. Women who are not good candidates for hormone therapy do not need to suffer in silence. There are many nonhormonal options to treat menopause symptoms.

4. Question: Are women who take oral contraceptives at an increased risk for cardiovascular disease?

Dr. Shufelt: Oral contraceptives are the most commonly prescribe hormones with approximately 80 percent of women in the U.S. using them at some point. In healthy younger women – young than 35 and nonsmokers – oral contraceptives do not increase a woman’s risk for heart disease. And we know that birth control pills can be helpful in controlling symptoms around perimenopause. That’s why you should re-read my answer to the first question and get to know your heart health numbers!

5. Question: Is it possible to treat menopause symptoms while simultaneously preventing heart disease?

Dr. Shufelt: Yes. That is exactly what we do at the Women’s Heart Center at the Cedars-Sinai Heart Institute. And it’s why menopause transition is such an important time for all women. I want women to know that when they reach menopause, it’s time to take stock of their health and their individual risk factors. Because when we know a patient’s numbers, we can help her assess the side effects and risks that come with all treatments and also help ensure that the second act of her life can be just as vibrant and active as the first.

6. Question: Does estrogen provide heart protection?

Dr. Shufelt: No, estrogen is not prescribed to prevent heart disease.

7. Question: What else should women know about heart disease?

Dr. Shufelt: When it comes to heart disease, women need to recognize that often, our symptoms are different from men’s heart disease symptoms. In addition to chest pain, women are more likely to have shortness of breath as a first sign of heart disease. Women more commonly experience extreme fatigue and persistent chest pain. Unlike men, women generally have major arteries that are clear of plaque, but the smaller coronary blood vessels cease to constrict and dilate properly, creating the lack of blood flow and oxygen to the heart.

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Posted in ask the expert, hormones

Is Botox safe if you have allergies?

Expert: Dr. Carlin Vickery

Partner, 5th Avenue Millennium Aesthetic Surgery
Associate Clinical Professor in Department of Surgery at Mount Sinai Medical Center

Ranked as one of NYC’s top board certified plastic surgeons, Dr. Vickery was one of the first women to train in plastic surgery and reconstructive microsurgery.  Dedicated to innovation throughout her 30 year career, she continues to use cutting edge techniques to achieving long lasting, optimal, aesthetic improvement of the breast, body and face.

Dear Dr. Vickery,

I am 49 and have terrible frown lines between my eyes.  Suffering from bad allergies (Penicillin, aspirin, Cipro and many others), and environmental substances (dander, dust, pollen), is Botox a safe option?

In all likelihood, Botox will be an excellent and safe option for your frown lines.  Reported allergic reactions are limited to patients with a sensitity to Albumin and to those who have already been exposed to Botox and have showed sensitivity.  Many patients with the allergies you describe have successfully had Botox treatment.  Discuss your concerns with a qualified physician, and if you want to be cautious, you could always have a small test dose before you have a full treatment.  Good Luck!

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How to Find Reliable Health Information Online

iStock_000000863840XXXSmallDear Staness,

I am so confused! There is so much conflicting information online about menopause and tests. One website says buy saliva tests to check my hormone levels for $299, and another says these are not good tests and a waste of money. Where do I go for dependable information?

Confused in Connecticut

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Dear Confused,

This is a GREAT question! I was shocked at the amount of misinformation online too. The Menopause Makeover co-author Dr. Wendy Klein led me to reliable information sources.

Since menopause is a natural transition, most of us are searching for “natural” management options.

If a website is selling a product, you can bet there will be editorial material supporting their product. How do you know if you can trust what you are reading?

Enter center stage – our leading lady to save the day: science.

The word science comes from the Latin “scientia,” meaning knowledge. Science refers to a system of acquiring knowledge.

Many people associate science with the medical community, and make the assumption that alternative methods are not supported. This is not true.

There are excellent, non-commercial resources supported by science that provide sound information on alternative, complementary and medical menopause treatment options. They are not selling anything. These resources are available to provide you with information supported by scientific research… knowledge based on concerted human effort to understand, or to understand better, the natural world and how the natural world works, with observable evidence as the basis of that understanding.

The North American Menopause Society is a professional, non-profit organization. To find your answer about hormone saliva testing, go to The North American Menopause Society and enter “hormone testing.”

“Saliva testing to determine if a woman has the “right amount” of hormones has not been proven accurate or reliable. Even blood testing of hormone levels has the drawback that levels vary throughout the day as well as from day to day. More important, the desired levels in postmenopausal women have not been established. In addition, an individual woman’s physical comfort may not even be related to her absolute hormone levels.”

On any website, it is wise to read the “About Us” link so you know WHO is providing the information. Generally, non-commercial websites make that information readily available so you can see the credentials and expertise of the people who are providing your advice.

We are all different. Work closely with your healthcare provider to discuss menopause treatment options specific to you.

Dr. Klein says, “Know where your medical health information is coming from, and don’t trust the biased medical information on websites that are selling products.”

I applaud your efforts to get educated on menopause matters. Gather information from reliable sources. My favorites are listed below.

Staness

Reliable resources that are unbiased and supported by science

North American Menopause Society

National Institutes of Health

The National Library of Medicine
MedlinePlus

American College of Obstetricians and Gynecologists

Centers for Disease Control and Prevention?

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Perimenopausal Depression

Wendy Klein MD150Are you suffering from hopelessness, apprehension, and deep sadness for prolonged periods? If so, you may be suffering from depression. During my menopause transition I felt blue for no reason at all. I could not snap out of it, and my friends and family were mystified.

Most perimenopausal women do not experience major depression, but many have symptoms of feeling depressed, stressed, and anxious.

If you are experiencing menopausal symptoms such as severe hot flashes and lack of sleep from night sweats, it may be causing you to feel depressed. Are you in a depressed mood and feeling sad, or are you suffering from clinical depression resulting from a chemical imbalance in the brain?

I recently teamed up with leading menopause expert and co-author of The Menopause Makeover, Dr. Wendy Klein, to get the latest scientific information on perimenopausal depression.

Perimenopause Depression Interview

Staness: What are the most common signs of depression?

Dr. Klein: The most common signs of depression are feeling sad, feeling worthless and losing interest in the things that normally engage you. Having no “get up and go,” you would rather sit on the couch doing nothing than get up and do something that would normally engage you. Other symptoms include the loss of libido, changes in appetite – too much or too little – feeling very sleepy and tired and fatigued, or having insomnia, not being able to sleep. A common sign of depression is a change in your normal habits.

A more serious symptom of depression is sustained loss of interest in things that you just can’t seem to break out of, which is called dysthymia. Things seem really bleak and you just can’t quite punch your way out of this paper bag of darkness and it lingers. If it lingers or if you have thoughts that are scary, such as wanting to give up or wanting to hurt yourself or even suicidal thoughts, you must talk to your clinician because there are things that can be done to help you.

Staness: What can cause these feelings of depression during menopause?

Dr. Klein: Depression is multi-factorial. There are many factors that can cause an increased risk for depression. If you have depression in your family, a prior history of depression, and even some medications can cause an increased risk of depression. Certain endocrine disorders, such as hypothyroidism, or other illnesses, such as chronic fatigue syndrome, are also associated with depression.

Depression is an illness that can be triggered by the chemicals in your brain. Serotonin regulates your moods. It is the “feel good” hormone. When serotonin levels drop you can experience extreme episodes of depression.

You also want to look at lifestyle stressors – a change in relationship, finances, loss of a loved one, caring for parents – and consider the many modalities of treatment that are available to help you.

You approach depression in menopause the same way that you would approach depression at any other time: you first want to rule out other medical causes, or other medications that might be contributing.

Staness: Many women live with daily stress and then throw in menopause and a few medications, and it is no surprise menopausal women may suffer from depression. What depression treatment options are available?

Dr. Klein: A number of options are available, including psychotherapy, and antidepressants and can assist you if you are suffering from depression.

There are degrees of depression. Mild depression, feeling blue or sad, can be dealt with cognitive therapy, psychotherapy, meditation, yoga, eating healthfully, and exercise. We know that exercise does boost your endorphins and can lift your mood. Also, engaging in new activities may help, such as making yourself take classes, making yourself get out and do things, and enlisting the support of your family and friends.

If you have lingering or worsening symptoms, you may need medication, because we know that depression can be a malfunction of your neurotransmitters, particularly serotonin, which is the feel good neurotransmitter. Medicines can be enormously helpful, although you will want to incorporate lifestyle changes as well.

In short, if someone is experiencing the signs or symptoms of depression, there are number of things you can do. Eating healthfully, exercising regularly, and seeking support from family and friends may help. Also, you can engage in any activity that gives you a sense of achievement. It may be taking a class, taking up something new such as yoga, or trying the drawing class that you always wanted to take, or volunteering and getting outside yourself. All of these things are very useful.

If you are still feeling very stuck and sad, talk to your clinician so you can get a referral to a good psychotherapist. If you need medication, in the broader context of menopausal symptoms, there is some evidence that hormone therapy can augment treatment and help people who are on anti-depressants feel even better. That is a decision for you and your clinician.

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If you suffer from depression or someone you love is depressed, get support, visit your health care provider and discuss your options for treating depression.

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Suffering from Hot Flashes?

hormonesResize2Hot Flash 101

The most common and often the most irritating symptom associated with menopause is the hot flash. As many as 75 percent of women going through menopause in the United States experience hot flashes with 10% to 15% of women having severe or frequent hot flashes. I had miserable hot flashes that heated up at the most inconvenient times and sometimes flaring up every few hours. I tried every trick in the book to eliminate this miserable symptom – from herbs, to teas, to exercise, to diet, to praying hourly that they would disappear – but they persisted.

With confusing and conflicting information online and in best-selling books, I teamed up with leading menopause expert and co-author of The Menopause Makeover, Dr. Wendy Klein, to get the latest scientific information on alternative, complementary and medical options to relieve hot flashes.

Understanding available hot flash options will give you the opportunity to discuss menopause management with your clinician. This interview with Dr. Klein is the first in a series that addresses the various menopause symptoms.

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Hot Flash Interview

Staness: Dr. Klein, what exactly is a hot flash?

Dr. Klein: A hot flash is a sensation of extreme heat in the head and upper body generally associated with sweating.

We know from studying women that the internal core temperature does increase. You can a put a sensor on the skin and before a woman experiences a hot flash she will be able to tell you, “I am going to have a hot flash.” And sure enough, there will be an increase in internal core temperature followed by profuse sweating which is very uncomfortable. As you know, the purpose of sweating is to cool the body so there is often a reflex of sort of chill that follows the hot flash. It is a very uncomfortable and distracting sensation. It can occur at any time of the day. It can occur with tremendous variability, it can happen many times an hour or only just once or twice a day. Some women have one or two hot flashes a day, and get through menopause with no problems while other women have fifteen or twenty a day. We are all different.

Staness: What causes a hot flash?

Dr. Klein: We are still trying to understand exactly what causes hot flashes. We know that they are related to the hypothalamus, which is in the center of the brain and acts like the thermostat for the body. What we don’t understand is why some women are so troubled by them and others are not.

Certain women seem to have triggers. An alcoholic beverage may bring on a hot flash, or a change in external temperature can cause a hot flash for some women. In general, the hormonal flux or variation in hormone levels seems to be related to this sensation in some women.

Staness: Are there other causes?

Dr. Klein: We know that smoking is associated with hot flashes. Women who smoke have a higher risk of troublesome hot flashes, so obviously you should not smoke.

Also certain medicines can cause hot flashes such as certain antidepressants SSRI, Selective Serotonin Reuptake Inhibitors, are common antidepressants that can actually cause an increase in hot flashes. Yet, for some women, a very low dose can actually alleviate hot flashes, making antidepressants an alternative to hormone therapy.

Illnesses and fever can cause hot flashes, as can malignancies, and tuberculosis – many illnesses can cause hot flashes.

Increased BMI, Body Mass Index, has been associated with hot flashes. We used to think that women who were heavy had excess estrogen, and therefore fewer hot flashes. Now from the major study that was done in the SWAN, Study of Women Across the Nation, we know that women who are heavy, who have abnormally high body mass index, are at increased risk for hot flashes.

Staness: What’s a menopausal gal to do if she suffers from hot flashes?

Dr. Klein: The real issue is how troubled are you. Some women find that they can manage their hot flashes with simple lifestyle changes, such as wearing layered clothing, lowering the thermostat, carrying a fan, drinking cool beverages, avoiding triggers like caffeine and alcohol. Some women can have a few hot flashes a day and over time, seventy-five to eighty percent of cases the hot flashes will diminish and disappear. Then there is a subset of women for whom hot flashes are really troubling and don’t go away. Lots of women have recurring hot flashes waking them up over and over again and they can’t go back to sleep. They are not getting enough rest; they wake up grouchy, tired, and sweaty. If it is really a problem, there are hormonal therapies that will alleviate these symptoms. As you know hormone therapy can have side effects, so you must always weigh the benefit versus the risk. There are very low dose hormone therapies that are now available that can be extremely useful for alleviating hot flashes.

There are some other options to consider such as soy and black cohosh. The studies regarding soy are mixed, with some showing that soy can be helpful; while there are other studies that show soy may help with mild symptoms. Soy is benign and easily available and may be worth trying. Black cohosh is another herb and has been used in Europe widely, but you have to be careful because there have been reports of toxicity with high doses. Used in limited amounts in standardized doses black cohosh supplements may help some women with hot flashes. Again, there have been mixed studies, so whatever you do, and with anything you take, you should always discuss with your clinician.

You can also try lifestyle changes – wearing layered clothing, practice deep breathing, meditation and yoga, exercising – all of these things that can be really helpful in learning to live with the symptoms if they are moderate.

Another option to treat hot flashes is gabapentin. This is a drug that was originally developed as an antiseizure medicine. Gabapentin is widely used for pain relief, because it was discovered that with patients in whom it was used for seizures, it helped with pain. It was then found that it helped with hot flashes. Gabapentin is a reasonable alternative to discuss with your clinician if you do not want to or if you cannot take hormone therapy.

Staness: I was on birth control pills for years and had no idea I was perimenopausal until I stopped them, then the hot flashes started erupting. Are birth control pills a good option for hot flashes?

Dr. Klein: Birth control pills are a form of hormone therapy. They are a higher dose than standard menopausal therapy, but there is estrogen in most birth control pills and that keeps hot flashes away. If you are in the perimenopausal phase, birth control pills can also be useful for regulating your periods, plus they keep hot flashes away.

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Understanding the causes and solutions for hot flashes is the first step to managing your menopause. If you suffer from hot flashes, discuss your treatment options (alternative, complementary and medical) with your healthcare provider.

If you need a certified menopause expert in your area, click here and enter your zip code.

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Should I take hormone therapy?

Expert:  Wendy Klein, M.D., co-author of The Menopause Makeover

Dear Dr. Klein,

HELP, I am so confused about hormone therapy after the latest headlines about breast cancer and hormones.  I had a hysterectomy 5 years ago, and my doctor prescribed the Vivelle patch 1.0 mg and I love it.  Should I stop using it?  I am afraid of getting breast cancer even though it does not run in my family. What should I do?

The headlines about breast cancer associated with hormone therapy use, although recent, do not really represent new data. We have known for many years that HT use  greater than 5 years increases breast cancer risk. That said, adverse effects are generally dose related, and all the research showing increased risk was done using doses of estrogen that are 3-4 times higher than what is used today.

The newest headlines reflect a long-term follow up of 2002 WHI results, in which it was found that prolonged use of estrogen and progesterone slightly increased the risk of breast cancer death. Of note is that this was not seen in women like yourself who, after hysterectomy, took estrogen only.

The best approach is to consult with a clinician who can help assess your risk for breast cancer by looking at personal medical history, family history, age, race and ethnicity, reproductive history, and history of breast biopsies. If you have no increased risk, then staying on estrogen for now may be appropriate. The answer in part depends upon personal considerations, such as the age at which you had your hysterectomy, your risk for bone loss, and how long you have been treated with estrogen.

Also, it is reasonable to consider very slowly lowering your dose of Vivelle, so that you are on the lowest effective dose. Above all, consult with your healthcare provider so that you can jointly make a thoughtful and carefully considered decision that meets your individual needs. There is no need to make sudden changes.

Living a healthy lifestyle, such as maintaining an ideal weight, not smoking, regular exercise, consuming low to medium glycemic carbohydrates, and limiting alcohol consumption can also help reduce your risk of breast cancer.

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Is perimenopause to blame for my kidney infection?

Expert: Wendy Klein, MD co-author of The Menopause Makeover

Dear Dr. Klein,

As you go through the change of life, is it normal for you to have an increase in bladder/urinary tract/kidney problems?

I had my first kidney infection in November. It was very painful and forced me to go to the ER. There was no warning and the symptoms hit me instantaneously. The doctors said it was a kidney infection and comes from a bladder infection left untreated. BUT I HAD NO SYMPTOMS.  They also said it comes from not drinking enough water or not going to the bathroom enough.  I work in an office, sitting all day for 8 hours.

I’m really baffled as to why I’m having urinary problems now, when nothing has changed in my lifestyle except the onset of perimenopause.

Answer: Many women have recurrent bladder infections, and, as you have already learned, untreated bladder infections can track up the urinary tract and lead to kidney infections. Not good. What you can do to prevent these -

1) Stay hydrated. Keep water with you at work & drink through the day.
2) Do not delay when you feel the need to urinate! Empty your bladder regularly and do not hold your urine.
3) If possible, empty your bladder after sex. Although difficult to prove, there is anecdotal evidence that urinating after sex may help to “wash away” bacteria.
4) Have a healthcare provider dipstick your urine at the first sign of problems to rule out an infection. If your bladder is infected, white blood cells will show up on your dipstick test, indicating a need for antibiotics. If there are no white blood cells, and you are having pain with urination, this may be a sign of low estrogen, which is easily treated with vaginal estrogen tablets or cream.

Also, if there is a history of diabetes in your family, have your blood sugar checked. New onset of recurring bladder or kidney infections can be a sign of diabetes.

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Irregular Periods During Perimenopause

Wendy Klein MD150One of the first symptoms you may notice during perimenopause is irregular periods.

Interview with Dr. Wendy Klein, leading menopause expert and co-author of The Menopause Makeover

Staness: What is one of the first symptoms of perimenopause?

Dr. Klein: The hallmark of perimenopause, which is the phase prior to menopause, is irregularity. We all grow up thinking that when you enter the change of life and become menopausal, your periods just stop. That is not the case.

What happens is your periods start to become irregular. You can have too many periods, you can have too few, you may skip a period and then get regular again, and you may skip a few periods. You may think, “oh my, I am in menopause,” and suddenly your period comes back again.

Staness: Why does this happen?

Dr. Klein: Prior to menopause your periods are usually very regular. The amount of hormone that you are producing is very regular and predictable. However, as you approach menopause, entering the perimenopausal phase, the ovaries are unpredictable. You will have months when you don’t ovulate, and that causes irregular bleeding.

Staness: How long does period irregularity last?

Dr. Klein: How long that lasts is highly individual. Could be a year, could be two years, could be three years and that is all normal variation. I like to say that the ovaries are stuttering. You don’t always ovulate and your previous hormonal milieu begins to change.

Eventually you will experience fewer periods and finally your periods will stop. You are not officially in menopause until you have skipped 12 consecutive periods.

Staness: How does a woman know her periods are irregular?

Dr. Klein: You may get too many periods. You may get too few. You may skip them. The bleeding may become heavier, or it can become lighter.

Staness: What should a perimenopausal woman with irregular periods do?

Dr. Klein: Well the easiest thing to do is keep track of your periods. Write them down in the your calendar and track them. Keep a record of when you are having your periods and what your symptoms are, so when you visit your clinician you can discuss the changes using actual dates.

If you are troubled by irregular periods, you can discuss the option of low dose birth control pills. This can help with regulation, with excessive flow, and also with contraception.

One of the issues of which you should be aware is that even in perimenopause you can still become pregnant and since your periods are not regular you have an increased risk of unintended pregnancy. Birth control is still necessary as long as you continue to ovulate, even if you are irregular.

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Menopause is a normal and natural part of a woman’s life. Arm yourself with knowledge, build a strong relationship with your clinician and manage your menopause empowered.

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My husband’s libido is disappearing, why?

Expert: Ernst Schwarz, M.D., Ph.D.
Director of Multi-disciplinary Heart Failure Research, Cedars-Sinai Heart Institute

Dear Dr. Schwarz,

Now my menopause symptoms are finally under control, something seems to be going on with my husband of 27 years. We used to have a great sex life but now his performance isn’t what it used to be. I have read that he should see a doctor to rule out any physical health issues. But what kind of doctor? And what kind of health problem could be causing this?

Although I can’t diagnose your husband based on an email, I can tell you that it might be a good idea to make an appointment with a cardiologist for a thorough check-up.

You say you have been married 27 years, so your husband probably is getting to the age when a heart check-up is appropriate. Also, reduced sexual performance capabilities can be a warning sign that a man is suffering from a heart or circulation (vascular) problem.

The main underlying cause is unhealthy changes in the functioning of the blood vessels carrying blood to the penis. That condition, called endothelial dysfunction, can be an early sign for underlying vascular diseases and conditions that can affect the heart and the brain among other organs.

Risk factors include diabetes, uncontrolled high blood pressure, elevated cholesterol and triglycerides, smoking and chronic alcohol or drug abuse. Endothelial dysfunction also can be a side effect of many medications, in particular medications to control blood pressure or treat depression.

Erectile dysfunction affects an estimated 30 million to 50 million U.S. men and can be successfully treated in most cases. But treatment requires letting your doctor know and men often shy away from admitting sexual problems to their doctors. That’s why many of my male patients hesitate to make the appointment. They finally come to see me when their wives become aware of the link between health issues and impotence and call my office to schedule an exam.

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Am I menopausal yet?

ShufeltC-CardioSMALLExpert: Chrisandra Shufelt, M.D.
Assistant Director of the Women’s Heart Center
at the Cedars-Sinai Heart Institute.

Dr. Shufelt is a certified menopause practitioner and a women’s health expert.

Dear Dr. Shufelt: I am 52 and there is no end in sight to my menstrual cycle. Shouldn’t I have stopped by now?

Like every woman, you should see your healthcare provider every year because annual Pap smears are important in detecting cervical cancer and yearly blood tests help keep track of your heart health. If your menstrual bleeding is prolonged or erratic, make an appointment to have yourself checked. During your period, if you are feeling lightheaded or short of breath, it could be a sign of too much bleeding, so get that checked out also.

But having regular periods at your age isn’t anything to be concerned about. In the United States, the average age for menopause is 51 for non-smokers and 50 for current and past smokers. By age 55, 95 percent of U.S. women will have reached menopause.

Still, if you want to see where you stand, ask your healthcare provider for a blood test to detect the amount of Follicle Stimulating Hormone or FSH. A rise in FSH is the first measurable sign that a woman is entering menopause.

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Posted in ask the expert, hormones
 
The ultimate guide to taking control of your health and beauty during menopause